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KMID : 0191120130280091394
Journal of Korean Medical Science
2013 Volume.28 No. 9 p.1394 ~ p.1398
An Infant with Prenatally Diagnosed Congenital Anaplastic Astrocytoma Who Remains Disease-Free after Proton Therapy
Shin Hyun-Jung

Kwon Young-Joo
Park Hyeon-Jin
Park Byung-Kiu
Shin Sang-Hoon
Kim Joo-Young
Lee Sang-Hyun
Kim Heung-Sik
Kim Dong-Won
Abstract
The authors present a rare of prenatally diagnosed congenital anaplastic astrocytoma. A 9-month-old boy had three recurrences despite two surgical resections and various chemotherapeutic regimens. He underwent the 3rd gross tumor removal at 11 months of age, followed by proton therapy, and now he remains disease-free for 3 yr without a significant neurocognitive dysfunction. This is the 1st case of a pediatric tumor treated by proton therapy in Korea, and proton therapy may be a treatment of choice for a congenital anaplastic astrocytoma in infants and young children, considering limitation of radiation therapy.
KEYWORD
Congenital Anaplastic Astrocytoma, Proton Therapy, Recurrence
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